Dynamique de l’ARN et systèmes biomoléculaires


Hervé Isambert Chef d'équipe Tél :

Voir la page de l’equipe Isambert here

Our research concerns the reconstruction, analysis and evolution of biomolecular networks at different scales and their implication on the organisms’ susceptibility to genetic diseases such as cancer. We develop quantitative statistical methods and computational tools to infer and analyze causal graphical models from biological data.

Publications clés

Année de publication : 2015

Param Priya Singh, Jatin Arora, Hervé Isambert (2015 Jul 17)

Identification of Ohnolog Genes Originating from Whole Genome Duplication in Early Vertebrates, Based on Synteny Comparison across Multiple Genomes.

PLoS computational biology : e1004394 : DOI : 10.1371/journal.pcbi.1004394

Année de publication : 2014

Param Priya Singh, Séverine Affeldt, Giulia Malaguti, Hervé Isambert (2014 Jul 31)

Human dominant disease genes are enriched in paralogs originating from whole genome duplication.

PLoS computational biology : e1003754 : DOI : 10.1371/journal.pcbi.1003754

Année de publication : 2012

Param Priya Singh, Séverine Affeldt, Ilaria Cascone, Rasim Selimoglu, Jacques Camonis, Hervé Isambert (2012 Apr 12)

On the expansion of « dangerous » gene repertoires by whole-genome duplications in early vertebrates.

Cell reports : 1387-98 : DOI : 10.1016/j.celrep.2012.09.034

Année de publication : 2009

Bastien Cayrol, Claude Nogues, Alexandre Dawid, Irit Sagi, Pascal Silberzan, Hervé Isambert (2009 Oct 14)

A nanostructure made of a bacterial noncoding RNA.

Journal of the American Chemical Society : 17270-6 : DOI : 10.1021/ja906076e

Année de publication : 2008

Kirill Evlampiev, Hervé Isambert (2008 Jul 16)

Conservation and topology of protein interaction networks under duplication-divergence evolution.

Proceedings of the National Academy of Sciences of the United States of America : 9863-8 : DOI : 10.1073/pnas.0804119105

Année de publication : 2007

M Cosentino Lagomarsino, P Jona, B Bassetti, H Isambert (2007 Mar 19)

Hierarchy and feedback in the evolution of the Escherichia coli transcription network.

Proceedings of the National Academy of Sciences of the United States of America : 5516-20
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