La présentation antigénique dans les cellules dendritiques

Membres de l’équipe

Sebastian Amigorena, PhD

Sebastian AMIGORENA - credit Thibaut Voisin 1 copie copie

Sebastian Amigorena Directeur de recherche CNRS Equipe Amigorena Directeur d'unité Chef d'équipe Tél : Retour à la liste

Publications clés

Année de publication : 2017

Christel Goudot, Alice Coillard, Alexandra-Chloé Villani, Paul Gueguen, Adeline Cros, Siranush Sarkizova, Tsing-Lee Tang-Huau, Mylène Bohec, Sylvain Baulande, Nir Hacohen, Sebastian Amigorena, Elodie Segura (2017 Sep 21)

Aryl Hydrocarbon Receptor Controls Monocyte Differentiation into Dendritic Cells versus Macrophages.

Immunity : 582-596.e6 : DOI : S1074-7613(17)30374-6
Andrés Alloatti, Derek C Rookhuizen, Leonel Joannas, Jean-Marie Carpier, Salvador Iborra, Joao G Magalhaes, Nader Yatim, Patrycja Kozik, David Sancho, Matthew L Albert, Sebastian Amigorena (2017 Jul 1)

Critical role for Sec22b-dependent antigen cross-presentation in antitumor immunity.

The Journal of experimental medicine : 2231-2241 : DOI : 10.1084/jem.20170229
Cerboni S, Jeremiah N, Gentili M, Gehrmann U, Conrad C, Stolzenberg MC, Picard C, Neven B, Fischer A, Amigorena S, Rieux-Laucat F, Manel N (2017 May 8)

Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes

The Journal of Experimental Medicine : DOI : 10.1084/jem.20161674

Année de publication : 2016

Christine Sedlik, Adèle Heitzmann, Sophie Viel, Rafik Ait Sarkouh, Cornélie Batisse, Frédéric Schmidt, Philippe De La Rochere, Nathalie Amzallag, Eduardo Osinaga, Pablo Oppezzo, Otto Pritsch, Xavier Sastre-Garau, Pascale Hubert, Sebastian Amigorena, Eliane Piaggio (2016 Sep 14)

Effective antitumor therapy based on a novel antibody-drug conjugate targeting the Tn carbohydrate antigen.

Oncoimmunology : e1171434 : DOI : 10.1080/2162402X.2016.1171434

Année de publication : 2015

Alloatti A1, Kotsias F2, Pauwels AM3, Carpier JM, Jouve M, Timmerman E, Pace L, Vargas P, Maurin M, Gehrmann U, Joannas L, Vivar OI, Lennon-Duménil AM, Savina A, Gevaert K, Beyaert R, Hoffmann E, Amigorena S. (2015 Dec 15)

Toll-like Receptor 4 Engagement on Dendritic Cells Restrains Phago-Lysosome Fusion and Promotes Cross-Presentation of Antigens.

Immunity : DOI : 10.1016/j.immuni.2015.11.006

Année de publication : 2012

Luigia Pace, Andy Tempez, Catharina Arnold-Schrauf, Fabrice Lemaitre, Philippe Bousso, Luc Fetler, Tim Sparwasser, Sebastian Amigorena (2012 Nov 1)

Regulatory T cells increase the avidity of primary CD8+ T cell responses and promote memory.

Science (New York, N.Y.) : 532-6 : DOI : 10.1126/science.1227049
Olivier P Joffre, Elodie Segura, Ariel Savina, Sebastian Amigorena (2012 Jul 13)

Cross-presentation by dendritic cells.

Nature reviews. Immunology : 557-69 : DOI : 10.1038/nri3254
Elodie Segura, Maxime Touzot, Armelle Bohineust, Antonio Cappuccio, Gilles Chiocchia, Anne Hosmalin, Marc Dalod, Vassili Soumelis, Sebastian Amigorena (2012 May 11)

Human inflammatory dendritic cells induce Th17 cell differentiation.

Immunity : 336-48 : DOI : 10.1016/j.immuni.2012.10.018

Année de publication : 2011

Ignacio Cebrian, Geraldine Visentin, Nicolas Blanchard, Mabel Jouve, Alexandre Bobard, Catarina Moita, Jost Enninga, Luis F Moita, Sebastian Amigorena, Ariel Savina (2011 May 17)

Sec22b regulates phagosomal maturation and antigen crosspresentation by dendritic cells.

Cell : 1355-68 : DOI : 10.1016/j.cell.2011.11.021

Année de publication : 2009

Matias Ostrowski, Nuno B Carmo, Sophie Krumeich, Isabelle Fanget, Graça Raposo, Ariel Savina, Catarina F Moita, Kristine Schauer, Alistair N Hume, Rui P Freitas, Bruno Goud, Philippe Benaroch, Nir Hacohen, Mitsunori Fukuda, Claire Desnos, Miguel C Seabra, François Darchen, Sebastian Amigorena, Luis F Moita, Clotilde Thery (2009 Aug 14)

Rab27a and Rab27b control different steps of the exosome secretion pathway.

Nature cell biology : 19-30; sup pp 1-13 : DOI : 10.1038/ncb2000