Bioinformatique et biologie des systèmes du cancer

Membres de l’équipe

Emmanuel Barillot, PhD

Emmanuel arillot

Emmanuel Barillot Chef d'équipe Equipe Barillot Directeur d'unité Chef d'équipe Tél : Retour à la liste

Publications clés

Année de publication : 2017

Maud Borensztein, Laurène Syx, Katia Ancelin, Patricia Diabangouaya, Christel Picard, Tao Liu, Jun-Bin Liang, Ivaylo Vassilev, Rafael Galupa, Nicolas Servant, Emmanuel Barillot, Azim Surani, Chong-Jian Chen, Edith Heard (2017 Jan 31)

Xist-dependent imprinted X inactivation and the early developmental consequences of its failure.

Nature structural & molecular biology : DOI : 10.1038/nsmb.3365

Année de publication : 2016

Wael Jdey, Sylvain Thierry, Christophe Russo, Flavien Devun, Muthana Al Abo, Patricia Noguiez-Hellin, Jian-Sheng Sun, Emmanuel Barillot, Andrei Zinovyev, Inna Kuperstein, Yves Pommier, Marie Dutreix (2016 Aug 26)

Drug Driven Synthetic Lethality: bypassing tumor cell genetics with a combination of Dbait and PARP inhibitors.

Clinical cancer research : an official journal of the American Association for Cancer Research : DOI : clincanres.1193.2016

Année de publication : 2014

Maia Chanrion, Inna Kuperstein, Cédric Barrière, Fatima El Marjou, David Cohen, Danijela Vignjevic, Lev Stimmer, Perrine Paul-Gilloteaux, Ivan Bièche, Silvina Dos Reis Tavares, Giuseppe-Fulvio Boccia, Wulfran Cacheux, Didier Meseure, Silvia Fre, Loredana Martignetti, Patricia Legoix-Né, Elodie Girard, Luc Fetler, Emmanuel Barillot, Daniel Louvard, Andreï Zinovyev, Sylvie Robine (2014 Apr 9)

Concomitant Notch activation and p53 deletion trigger epithelial-to-mesenchymal transition and metastasis in mouse gut.

Nature communications : 5005 : DOI : 10.1038/ncomms6005
Anne Biton, Isabelle Bernard-Pierrot, Yinjun Lou, Clémentine Krucker, Elodie Chapeaublanc, Carlota Rubio-Pérez, Nuria López-Bigas, Aurélie Kamoun, Yann Neuzillet, Pierre Gestraud, Luca Grieco, Sandra Rebouissou, Aurélien de Reyniès, Simone Benhamou, Thierry Lebret, Jennifer Southgate, Emmanuel Barillot, Yves Allory, Andrei Zinovyev, François Radvanyi (2014 Jan 25)

Independent component analysis uncovers the landscape of the bladder tumor transcriptome and reveals insights into luminal and basal subtypes.

Cell reports : 1235-45 : DOI : 10.1016/j.celrep.2014.10.035

Année de publication : 2013

Andrei Zinovyev, Inna Kuperstein, Emmanuel Barillot, Wolf-Dietrich Heyer (2013 Dec 14)

Synthetic lethality between gene defects affecting a single non-essential molecular pathway with reversible steps.

PLoS computational biology : e1003016 : DOI : 10.1371/journal.pcbi.1003016
Haitham Ashoor, Aurélie Hérault, Aurélie Kamoun, François Radvanyi, Vladimir B Bajic, Emmanuel Barillot, Valentina Boeva (2013 Sep 9)

HMCan: a method for detecting chromatin modifications in cancer samples using ChIP-seq data.

Bioinformatics (Oxford, England) : 2979-86 : DOI : 10.1093/bioinformatics/btt524

Année de publication : 2012

Eric Bonnet, Laurence Calzone, Daniel Rovera, Gautier Stoll, Emmanuel Barillot, Andrei Zinovyev (2012 Sep 7)

BiNoM 2.0, a Cytoscape plugin for accessing and analyzing pathways using standard systems biology formats.

BMC systems biology : 18 : DOI : 10.1186/1752-0509-7-18
Sofia I Bogiatzi, Maude Guillot-Delost, Antonio Cappuccio, Jean-Christophe Bichet, Olfa Chouchane-Mlik, Marie-Hélène Donnadieu, Emmanuel Barillot, Philippe Hupé, Katerina Chlichlia, Eleni I Efremidou, Selim Aractingi, Olivier Bayrou, Vassili Soumelis (2012 Mar 11)

Multiple-checkpoint inhibition of thymic stromal lymphopoietin-induced TH2 response by TH17-related cytokines.

The Journal of allergy and clinical immunology : 233-40.e5 : DOI : 10.1016/j.jaci.2012.04.038

Année de publication : 2011

Elphège P Nora, Bryan R Lajoie, Edda G Schulz, Luca Giorgetti, Ikuhiro Okamoto, Nicolas Servant, Tristan Piolot, Nynke L van Berkum, Johannes Meisig, John Sedat, Joost Gribnau, Emmanuel Barillot, Nils Blüthgen, Job Dekker, Edith Heard (2011 Oct 3)

Spatial partitioning of the regulatory landscape of the X-inactivation centre.

Nature : 381-5 : DOI : 10.1038/nature11049

Année de publication : 2010

Fariba Némati, Xavier Sastre-Garau, Cécile Laurent, Jérôme Couturier, Pascale Mariani, Laurence Desjardins, Sophie Piperno-Neumann, Olivier Lantz, Bernard Asselain, Corine Plancher, Delphine Robert, Isabelle Péguillet, Marie-Hélène Donnadieu, Ahmed Dahmani, Marie-Andrée Bessard, David Gentien, Cécile Reyes, Simon Saule, Emmanuel Barillot, Sergio Roman-Roman, Didier Decaudin (2010 Apr 6)

Establishment and characterization of a panel of human uveal melanoma xenografts derived from primary and/or metastatic tumors.

Clinical cancer research : an official journal of the American Association for Cancer Research : 2352-62 : DOI : 10.1158/1078-0432.CCR-09-3066

Année de publication : 2009

Laurence Calzone, Laurent Tournier, Simon Fourquet, Denis Thieffry, Boris Zhivotovsky, Emmanuel Barillot, Andrei Zinovyev (2009 Aug 25)

Mathematical modelling of cell-fate decision in response to death receptor engagement.

PLoS computational biology : e1000702 : DOI : 10.1371/journal.pcbi.1000702
Elisabetta Volpe, Maxime Touzot, Nicolas Servant, Marie-Annick Marloie-Provost, Philippe Hupé, Emmanuel Barillot, Vassili Soumelis (2009 Aug 24)

Multiparametric analysis of cytokine-driven human Th17 differentiation reveals a differential regulation of IL-17 and IL-22 production.

Blood : 3610-4 : DOI : 10.1182/blood-2009-05-223768
Jennifer C Chow, Constance Ciaudo, Melissa J Fazzari, Nathan Mise, Nicolas Servant, Jacob L Glass, Matthew Attreed, Philip Avner, Anton Wutz, Emmanuel Barillot, John M Greally, Olivier Voinnet, Edith Heard (2009 Aug 21)

LINE-1 activity in facultative heterochromatin formation during X chromosome inactivation.

Cell : 956-69 : DOI : 10.1016/j.cell.2010.04.042