Recombinaison, Réplication et Stabilité du génome

Membres de l’équipe

Sarah Lambert, PhD

Sarah lambert

Sarah Lambert Directeur de Recherche CNRS Equipe Lambert Directrice Adjointe d'unité Chef d'équipe Tél : Retour à la liste

Publications clés

Année de publication : 2021

Antony Carr, Sarah Lambert (2021 Aug 4)

Recombination-dependent replication: new perspectives from site-specific fork barriers.

Current opinion in genetics & development : 129-135 : DOI : S0959-437X(21)00094-0
Charlotte Audoynaud, Stéphan Vagner, Sarah Lambert (2021 Jul 5)

Non-homologous end-joining at challenged replication forks: an RNA connection?

Trends in genetics : TIG : DOI : S0168-9525(21)00166-9
Karol Kramarz, Anissia Ait Saada, Sarah A E Lambert (2021 Jan 1)

The Analysis of Recombination-Dependent Processing of Blocked Replication Forks by Bidimensional Gel Electrophoresis.

Methods in molecular biology (Clifton, N.J.) : 365-381 : DOI : 10.1007/978-1-0716-0644-5_25

Année de publication : 2020

Karol Kramarz, Kamila Schirmeisen, Virginie Boucherit, Anissia Ait Saada, Claire Lovo, Benoit Palancade, Catherine Freudenreich, Sarah A E Lambert (2020 Nov 7)

The nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal.

Nature communications : 5643 : DOI : 10.1038/s41467-020-19516-z
Simon Gemble, Géraldine Buhagiar-Labarchède, Rosine Onclercq-Delic, Gaëlle Fontaine, Sarah Lambert, Mounira Amor-Guéret (2020 May 14)

Topoisomerase IIα prevents ultrafine anaphase bridges by two mechanisms.

Open biology : 190259 : DOI : 10.1098/rsob.190259
Lambert, S. Borde, V. Charbonnier, J. B. Dantzer, F. Espeli, O. Guirouilh-Barbat, J. Llorente, B. Legube, G. Prioleau, M. N. Radicella, P. (2020 Feb 1)

Des mécanismes moléculaires aux applications cliniques. L’essentiel du Colloque Réplication-Réparation-Recombinaison 2019

Bull Cancer : 283-287 : DOI : 10.1016/j.bulcan.2020.01.003

Année de publication : 2019

Julien Hardy, Dingli Dai, Anissia Ait Saada, Ana Teixeira-Silva, Louise Dupoiron, Fatemeh Mojallali, Karine Fréon, Francoise Ochsenbein, Brigitte Hartmann, Sarah Lambert (2019 Oct 4)

Histone deposition promotes recombination-dependent replication at arrested forks.

PLoS genetics : e1008441 : DOI : 10.1371/journal.pgen.1008441
Sarah Lambert (2019 Mar 3)

Unstable genomes promote inflammation.

Nature : 41-42 : DOI : 10.1038/d41586-019-00510-5

Année de publication : 2017

Ana Teixeira-Silva, Anissia Ait Saada, Julien Hardy, Ismail Iraqui, Marina Charlotte Nocente, Karine Fréon, Sarah A E Lambert (2017 Dec 7)

The end-joining factor Ku acts in the end-resection of double strand break-free arrested replication forks.

Nature communications : 1982 : DOI : 10.1038/s41467-017-02144-5
Anissia Ait Saada, Ana Teixeira-Silva, Ismail Iraqui, Audrey Costes, Julien Hardy, Giulia Paoletti, Karine Fréon, Sarah A E Lambert (2017 May 4)

Unprotected Replication Forks Are Converted into Mitotic Sister Chromatid Bridges.

Molecular cell : 398-410.e4 : DOI : 10.1016/j.molcel.2017.04.002

Année de publication : 2016

Simon Gemble, Géraldine Buhagiar-Labarchède, Rosine Onclercq-Delic, Denis Biard, Sarah Lambert, Mounira Amor-Guéret (2016 Aug 15)

A balanced pyrimidine pool is required for optimal Chk1 activation to prevent ultrafine anaphase bridge formation.

Journal of cell science : 3167-77 : DOI : 10.1242/jcs.187781

Année de publication : 2015

Simon Gemble, Akshay Ahuja, Géraldine Buhagiar-Labarchède, Rosine Onclercq-Delic, Julien Dairou, Denis S F Biard, Sarah Lambert, Massimo Lopes, Mounira Amor-Guéret (2015 Jul 16)

Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under Replication of DNA.

PLoS genetics : e1005384 : DOI : 10.1371/journal.pgen.1005384

Année de publication : 2014

Violena Pietrobon, Karine Fréon, Julien Hardy, Audrey Costes, Ismail Iraqui, Françoise Ochsenbein, Sarah A E Lambert (2014 Oct 14)

The chromatin assembly factor 1 promotes Rad51-dependent template switches at replication forks by counteracting D-loop disassembly by the RecQ-type helicase Rqh1.

PLoS biology : e1001968 : DOI : 10.1371/journal.pbio.1001968
Indiana Magdalou, Bernard S Lopez, Philippe Pasero, Sarah A E Lambert (2014 Jun 1)

The causes of replication stress and their consequences on genome stability and cell fate.

Seminars in cell & developmental biology : 154-64 : DOI : 10.1016/j.semcdb.2014.04.035
Martin Dutertre, Sarah Lambert, Aura Carreira, Mounira Amor-Guéret, Stéphan Vagner (2014 Mar 1)

DNA damage: RNA-binding proteins protect from near and far.

Trends in biochemical sciences : 141-9 : DOI : 10.1016/j.tibs.2014.01.003

Année de publication : 2013

Antony M Carr, Sarah Lambert, Aura Carreira (2013 Nov 29)

Replication stress-induced genome instability: the dark side of replication maintenance by homologous recombination.

Journal of molecular biology : 4733-44 : DOI : 10.1016/j.jmb.2013.04.023
Sarah Lambert, Antony M Carr (2013 Apr 1)

Replication stress and genome rearrangements: lessons from yeast models.

Current opinion in genetics & development : 132-9 : DOI : 10.1016/j.gde.2012.11.009
Sarah Lambert, Antony M Carr (2013 Mar 1)

Impediments to replication fork movement: stabilisation, reactivation and genome instability.

Chromosoma : 33-45 : DOI : 10.1007/s00412-013-0398-9