Membres de l’équipe
Marie-Paule Teulade-Fichou, PhD
Marie-Paule Teulade-Fichou Directeur de recherche CNRS Equipe Teulade-Fichou Chef d'équipe Tél :
Publications clés
Année de publication : 2020
Lei He, Zhenyu Meng, Qianqian Guo, Xiangyang Wu, Marie-Paule Teulade-Fichou, Edwin Kok Lee Yeow, Fangwei Shao (2020 Nov 28)
Fluorogenic Pt complexes distinguish the quantity and folding behavior of RNA G-quadruplexes between live cancerous and healthy cells.
Chemical communications (Cambridge, England) : 56 : 14459-14462 : DOI : 10.1039/d0cc05622g
Marchand A., Beauvineau C., Teulade-Fichou M.P., Zenobi R. (2020 Oct 14)
Competition of ligands and the 18-mer binding domain of the RHAU helicase for G-quadruplexes – orthosteric or allosteric binding mechanism?
Chemistry – A European Journal : Accepted article : DOI : 10.1002/chem.202004040
Paudel B.P., Moye A.L., Assi H.A., El-Khoury R., Cohen S.B., Birrento M.L., Samosorn S., Intharapichai K., Tomlinson C.G., Teulade-Fichou M.P., González C., Beck J.L., Damha M.J., van Oijen A.M., Bryan T.M. (2020 Jul 29)
A mechanism for the extension and unfolding of parallel telomeric G-quadruplexes by human telomerase at single-molecule resolution
eLife : 9 : e56428 : DOI : 10.7554/eLife.56428
Anton Granzhan, Rodrigo Prado Martins, Robin Fåhraeus, Marc Blondel and Marie-Paule Teulade-Fichou (2020 Jun 30)
Quadruplex-interacting compounds for regulating the translation of the Epstein–Barr virus nuclear antigen 1 (EBNA1) mRNA: A new strategy to prevent and treat EBV-related cancers
Quadruplex Nucleic Acids As Targets For Medicinal Chemistry, Annual Reports in Medicinal Chemistry : Chap 8, 54 : 243-286 : DOI : 10.1016/bs.armc.2020.05.001
Rahima Chennoufi, Ngoc-Duong Trinh, Françoise Simon, Guillaume Bordeau, Delphine Naud-Martin, Albert Moussaron, Bertrand Cinquin, Houcine Bougherara, Béatrice Rambaud, Patrick Tauc, Céline Frochot, Marie-Paule Teulade-Fichou, Florence Mahuteau-Betzer & Eric Deprez (2020 Apr 23)
Interplay between cellular uptake, intracellular localization and the cell death mechanism in triphenylamine-mediated photoinduced cell death
Scientific Reports : 10 : 6881 : DOI : 10.1038/s41598-020-63991-9
Abhijit Saha, Patricia Duchambon, Vanessa Masson, Damarys Loew, Sophie Bombard, Marie-Paule Teulade-Fichou (2020 Mar 20)
Nucleolin Discriminates Drastically between Long-Loop and Short-Loop Quadruplexes.
Biochemistry : 59 : 1261-1272 : DOI : 10.1021/acs.biochem.9b01094Année de publication : 2019
Angrand G., Quillévéré A., Loaëc N., Daskalogianni C., Granzhan A., Teulade-Fichou M.P., Fahraeus R., Prado Martins R., Blondel M. (2019 Sep 1)
Sneaking Out for Happy Hour: Yeast-Based Approaches to Explore and Modulate Immune Response and Immune Evasion
Genes : 10 : 667-689 : DOI : 10.3390/genes10090667
Michaela Krafcikova, Simon Dzatko, Coralie Caron, Anton Granzhan, Radovan Fiala, Tomas Loja, Marie-Paule Teulade-Fichou, Tomas Fessl, Robert Hänsel-Hertsch, Jean-Louis Mergny, Silvie Foldynova-Trantirkova, Lukas Trantirek (2019 Aug 9)
Monitoring DNA–Ligand Interactions in Living Human Cells Using NMR Spectroscopy
Journal of the American Chemical Society : 141 : 13281-13285 : DOI : 10.1021/jacs.9b03031
Xiao Xie, Michela Zuffo, Marie-Paule Teulade-Fichou, Anton Granzhan (2019 Aug 6)
Identification of optimal fluorescent probes for G-quadruplex nucleic acids through systematic exploration of mono- and distyryl dye libraries
Beilstein Journal of Organic Chemistry : 15 : 1872–1889 : DOI : 10.3762/bjoc.15.183
Paulina Prorok, Marie Artufel, Antoine Aze, Philippe Coulombe, Isabelle Peiffer, Laurent Lacroix, Aurore Guédin, Jean-Louis Mergny, Julia Damaschke, Aloys Schepers, Christelle Cayrou, Marie-Paule Teulade-Fichou, Benoit Ballester, Marcel Méchali (2019 Jul 24)
Involvement of G-quadruplex regions in mammalian replication origin activity.
Nature communications : 10 : 3274 : DOI : 10.1038/s41467-019-11104-0
Emilia Puig Lombardi, Allyson Holmes, Daniela Verga, Marie-Paule Teulade-Fichou, Alain Nicolas, Arturo Londoño-Vallejo (2019 Jul 9)
Thermodynamically stable and genetically unstable G-quadruplexes are depleted in genomes across species.
Nucleic acids research : 47 : 6098-6113 : DOI : 10.1093/nar/gkz463
Oksana Reznichenko, Alicia Quillévéré, Rodrigo Prado Martins, Nadège Loaëc, Hang Kang, María José Lista, Claire Beauvineau, Jorge González-García, Régis Guillot, Cécile Voisset, Chrysoula Daskalogianni, Robin Fåhraeus, Marie-Paule Teulade-Fichou, Marc Blondel, Anton Granzhan (2019 May 23)
Novel cationic bis(acylhydrazones) as modulators of Epstein–Barr virus immune evasion acting through disruption of interaction between nucleolin and G-quadruplexes of EBNA1 mRNA
European Journal of Medicinal Chemistry : 178 : 13-29 : DOI : 10.1016/j.ejmech.2019.05.042
Katerina Duskova, Jérémy Lamarche, Souheila Amor, Coralie Caron, Nicolas Queyriaux, Marie Gaschard, Marie-Jose Penouilh, Guillaume De Robillard, Dominique Delmas, Charles H Devillers, Anton Granzhan, Marie-Paule Teulade-Fichou, Murielle Chavarot-Kerlidou, Bruno Therrien, Sébastien Britton, David Monchaud (2019 Apr 3)
Identification of three-way DNA junction ligands through screening of chemical libraries and validation by complementary in vitro assays.
Journal of Medicinal Chemistry : 62 : 4456-4466 : DOI : 10.1021/acs.jmedchem.8b01978
Paul D., Marchand A., Verga D., Bombard S., Teulade-Fichou M.P., Rosu F., Gabelica V. (2019 Feb 28)
Probing Ligand and Cation Binding Sites in G-Quadruplex Nucleic Acids by Mass Spectrometry and Electron Photodetachment Dissociation Sequencing
Analyst : 144 : 3518-3524 : DOI : 10.1039/C9AN00398C
Delphine Naud-Martin, Corinne Landras-Guetta, Daniela Verga, Deepanjan Ghosh, Sylvain Achelle, Florence Mahuteau-Betzer, Sophie Bombard, Marie-Paule Teulade-Fichou (2019 Jan 26)
Selectivity of Terpyridine Platinum Anticancer Drugs for G-quadruplex DNA.
Molecules (Basel, Switzerland) : 24 : 404 : DOI : 10.3390/molecules24030404Année de publication : 2018
Prado Martins R., Findakly S., Daskalogianni C., Teulade-Fichou M.P., Blondel M., Fåhraeus R. (2018 Nov 29)
In Cellulo Protein-mRNA Interaction Assay to Determine the Action of G-Quadruplex-Binding Molecules
Molecules : 23 : 3124 : DOI : 10.3390/molecules23123124
Verga D., Nguyen C.H., Dakir M., Coll J.L., Teulade-Fichou M.P., Molla A. (2018 Nov 20)
Polyheteroaryl Oxazole/Pyridine-based compounds selected in vitro as G-quadruplex ligands inhibit Rock kinase and exhibit antiproliferative activity
Journal of Medicinal Chemistry : 61 : 10502-10518 : DOI : 10.1021/acs.jmedchem.8b01023
Hee-Sheung Lee, Mar Carmena, Mikhail Liskovykh, Emma Peat, Jung-Hyun Kim, Mitsuo Oshimura, Hiroshi Masumoto, Marie-Paule Teulade-Fichou, Yves Pommier, William C Earnshaw, Vladimir Larionov, Natalay Kouprina (2018 Nov 1)
Systematic Analysis of Compounds Specifically Targeting Telomeres and Telomerase for Clinical Implications in Cancer Therapy.
Cancer research : 78 : 6282-6296 : DOI : 10.1158/0008-5472.CAN-18-0894
Abhijit Saha, Sophie Bombard, Anton Granzhan, Marie-Paule Teulade-Fichou (2018 Oct 27)
Probing of G-Quadruplex Structures via Ligand-Sensitized Photochemical Reactions in BrU-Substituted DNA.
Scientific Reports : 8 : 15814 : DOI : 10.1038/s41598-018-34141-z
Filippo Doria, Valentina Pirota, Michele Petenzi, Marie-Paule Teulade-Fichou, Daniela Verga, Mauro Freccero (2018 Aug 30)
Oxadiazole/Pyridine-Based Ligands: A Structural Tuning for Enhancing G-Quadruplex Binding.
Molecules (Basel, Switzerland) : 23 : 2162 : DOI : 10.3390/molecules23092162
Xiao Xie, Oksana Reznichenko, Ludovic Chaput, Pascal Martin, Marie-Paule Teulade-Fichou, Anton Granzhan (2018 Aug 27)
Topology-Selective Fluorescent « Light-Up » Probes for G-Quadruplex DNA Based on Photoinduced Electron Transfer.
Chemistry - A European Journal : 24 : 12638-12651 : DOI : 10.1002/chem.201801701
Lina Saker, Samar Ali, Caroline Masserot, Guillaume Kellermann, Joel Poupon, Marie-Paule Teulade-Fichou, Evelyne Ségal-Bendirdjian, Sophie Bombard (2018 Jul 3)
Platinum Complexes Can Bind to Telomeres by Coordination.
International journal of molecular sciences : 19 : 1951 : DOI : 10.3390/ijms19071951
Aaron Mendez-Bermudez, Liudmyla Lototska, Serge Bauwens, Marie-Josèphe Giraud-Panis, Olivier Croce, Karine Jamet, Agurtzane Irizar, Macarena Mowinckel, Stephane Koundrioukoff, Nicolas Nottet, Genevieve Almouzni, Mare-Paule Teulade-Fichou, Michael Schertzer, Mylène Perderiset, Arturo Londoño-Vallejo, Michelle Debatisse, Eric Gilson, Jing Ye (2018 May 3)
Genome-wide Control of Heterochromatin Replication by the Telomere Capping Protein TRF2
Molecular cell : 70 : 449-461.e5 : DOI : 10.1016/j.molcel.2018.03.036
Ludivine Guyon, Marc Pirrotta, Katerina Duskova, Anton Granzhan, Marie-Paule Teulade-Fichou, David Monchaud (2018 Feb 16)
TWJ-Screen: an isothermal screening assay to assess ligand/DNA junction interactions in vitro
Nucleic Acids Research : 46 : e16 : DOI : 10.1093/nar/gkx1118
Hammerer F., Poyer F., Fourmois L., Chen S., Garcia G., Teulade-Fichou M.P., Maillard P., Mahuteau-Betzer F. (2018 Jan 1)
Mitochondria-targeted cationic porphyrin-triphenylamine hybrids for enhanced two-photon photodynamic therapy
Bioorganic & Medicinal Chemistry : 26 : 107-118 : DOI : 10.1016/j.bmc.2017.11.024Année de publication : 2017
Michelle Newman, Rym Sfaxi, Abhijit Saha, David Monchaud, Marie-Paule Teulade-Fichou, Stéphan Vagner (2017 Oct 27)
The G-Quadruplex-Specific RNA Helicase DHX36 Regulates p53 Pre-mRNA 3′-End Processing Following UV-Induced DNA Damage.
Journal of Molecular Biology : 429 : 3121-3131 : DOI : 10.1016/j.jmb.2016.11.033
Lista M.J., Martins R.P., Angrand G., Quillevere A., Daskalogianni C., Voisset C., Teulade-Fichou M.P., Fahraeus R., Blondel M. (2017 Sep 1)
A yeast model for the mechanism of the Epstein-Barr virus immune evasion identifies a new therapeutic target to interfere with the virus stealthiness
MICROBIAL CELL : 4 : 305-307 : DOI : 10.15698/mic2017.09.590
Claire Beauvineau, Corinne Guetta, Marie-Paule Teulade-Fichou, Florence Mahuteau-Betzer (2017 Aug 14)
PhenDV, a turn-off fluorescent quadruplex DNA probe for improving the sensitivity of drug screening assays
Organic & Biomolecular Chemistry : 15 : 7117-7121 : DOI : 10.1039/c7ob01705g
Jiyeon Choi, Mai Xu, Matthew M Makowski, Tongwu Zhang, Matthew H Law, Michael A Kovacs, Anton Granzhan, Wendy J Kim, Hemang Parikh, Michael Gartside, Jeffrey M Trent, Marie-Paule Teulade-Fichou, Mark M Iles, Julia A Newton-Bishop, D Timothy Bishop, Stuart MacGregor, Nicholas K Hayward, Michiel Vermeulen, Kevin M Brown (2017 Aug 1)
A common intronic variant of PARP1 confers melanoma risk and mediates melanocyte growth via regulation of MITF.
Nature genetics : 49 : 1326-1335 : DOI : 10.1038/ng.3927
Verga D., Hamon F., Nicoleau C., Guetta C., Wu T.-D., Guerquin-Kern J.-L., Marco S. & Teulade-Fichou M.-P. (2017 Jul 27)
Chemical Imaging by NanoSIMS Provides High- Resolution Localization of the G-Quadruplex Interactive Drug (Br)-PhenDC3 on Human Chromosomes
Journal of Molecular Biology and Molecular Imaging : 4 : 1029
Marie-Paule Teulade-Fichou, Joël Lefebvre, Corinne Guetta, Florent Poyer, Florence Mahuteau-Betzer (2017 Jul 13)
Copper-alkyne complexation is responsible for the Nucleolar Localisation of Quadruplex Nucleic Acid Drugs Labelled by Click Chemistry.
Angewandte Chemie (International ed. in English) : 56 : 11365-11369 : DOI : 10.1002/anie.201703783
María José Lista, Rodrigo Prado Martins, Olivier Billant, Marie-Astrid Contesse, Sarah Findakly, Pierre Pochard, Chrysoula Daskalogianni, Claire Beauvineau, Corinne Guetta, Christophe Jamin, Marie-Paule Teulade-Fichou, Robin Fåhraeus, Cécile Voisset, Marc Blondel (2017 Jul 8)
Nucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNA.
Nature communications : 8 : 16043 : DOI : 10.1038/ncomms16043
Razan Charif, Christine Granotier-Beckers, Hélène Charlotte Bertrand, Joël Poupon, Evelyne Ségal-Bendirdjian, Marie-Paule Teulade-Fichou, François D. Boussin, Sophie Bombard (2017 Jun 28)
Association of a Platinum Complex to a G-Quadruplex Ligand Enhances Telomere Disruption
Cheminal Research in Toxicology : 30 : 1629-1640 : DOI : 10.1021/acs.chemrestox.7b00131
Chennoufi R., Mahuteau-Betzer F., Tauc P., Teulade-Fichou M.P., Deprez E. (2017 Jun 18)
Triphenylamines Induce Cell Death Upon 2-Photon Excitation
Molecular Imaging : 16 : 1-4 : DOI : 10.1177/1536012117714164
Morgan Pellerano, Sergey Tcherniuk, Corine Perals, Thi Nhu Ngoc Van, Elsa Garcin, Florence Mahuteau-Betzer, Marie-Paule Teulade-Fichou, May C Morris (2017 Apr 22)
Targeting Conformational Activation of CDK2 Kinase.
Biotechnology journal : 12 : 1600531 : DOI : 10.1002/biot.201600531
Naoko Kotera, Régis Guillot, Marie-Paule Teulade-Fichou, Anton Granzhan (2017 Apr 4)
Copper(II)-Controlled Molecular Glue for Mismatched DNA.
ChemBioChem : 18 : 618-622 : DOI : 10.1002/cbic.201600675
Sébastien Lyonnais, Aleix Tarrés-Soler, Anna Rubio-Cosials, Anna Cuppari, Reicy Brito, Joaquim Jaumot, Raimundo Gargallo, Marta Vilaseca, Cristina Silva, Anton Granzhan, Marie-Paule Teulade-Fichou, Ramon Eritja, Maria Solà (2017 Mar 9)
The human mitochondrial transcription factor A is a versatile G-quadruplex binding protein.
Scientific reports : 7 : 43992 : DOI : 10.1038/srep43992
Guillaume Kellermann, Florent Dingli, Vanessa Masson, Daniel Dauzonne, Evelyne Ségal-Bendirdjian, Marie-Paule Teulade-Fichou, Damarys Loew, Sophie Bombard (2017 Mar 1)
Exploring the mechanism of inhibition of human telomerase by cysteine-reactive compounds.
FEBS letters : 591 : 863-874 : DOI : 10.1002/1873-3468.12589Année de publication : 2016
Naoko Kotera, Anton Granzhan, Marie-Paule Teulade-Fichou (2016 Aug 16)
Comparative study of affinity and selectivity of ligands targeting abasic and mismatch sites in dna using a fluorescence-melting assay.
Biochimie : 128-129 : 133-137 : DOI : 10.1016/j.biochi.2016.08.004
Jean-François Betzer, Frédérick Nuter, Mélanie Chtchigrovsky, Florian Hamon, Guillaume Kellermann, Samar Ali, Marie-Ange Calméjane, Sylvain Roque, Joël Poupon, Thierry Cresteil, Marie-Paule Teulade-Fichou, Angela Marinetti, Sophie Bombard (2016 Apr 27)
Linking of Antitumor trans NHC-Pt(II) Complexes to G-Quadruplex DNA Ligand for Telomeric Targeting.
Bioconjugate chemistry : 27 : 1456-70 : DOI : 10.1021/acs.bioconjchem.6b00079
Anne Cammas, Magali Lacroix-Triki, Sandra Pierredon, Morgane Le Bras, Jason S Iacovoni, Marie-Paule Teulade-Fichou, Gilles Favre, Henri Roché, Thomas Filleron, Stefania Millevoi, Stéphan Vagner (2016 Mar 29)
hnRNP A1-mediated translational regulation of the G quadruplex-containing RON receptor tyrosine kinase mRNA linked to tumor progression.
Oncotarget : 7 : 16793-16805 : DOI : 10.18632/oncotarget.7589
Morgan Pellerano, Delphine Naud-Martin, Marion Peyressatre, Camille Prével, Marie-Paule Teulade-Fichou, May Morris, Florence Mahuteau-Betzer (2016 Mar 17)
TP-2Rho Is a Sensitive Solvatochromic Red-Shifted Probe for Monitoring the Interactions between CDK4 and Cyclin D.
Chembiochem : a European journal of chemical biology : 17 : 737-744 : DOI : 10.1002/cbic.201500641
Rahima Chennoufi, Houcine Bougherara, Nathalie Gagey-Eilstein, Blaise Dumat, Etienne Henry, Frédéric Subra, Stéphanie Bury-Moné, Florence Mahuteau-Betzer, Patrick Tauc, Marie-Paule Teulade-Fichou, Eric Deprez (2016 Mar 8)
Mitochondria-targeted Triphenylamine Derivatives Activatable by Two-Photon Excitation for Triggering and Imaging Cell Apoptosis.
Scientific reports : 6 : 21458 : DOI : 10.1038/srep21458
Blaise Dumat, Elodie Faurel-Paul, Pauline Fornarelli, Nicolas Saettel, Germain Metgé, Céline Fiorini-Debuisschert, Fabrice Charra, Florence Mahuteau-Betzer, Marie-Paule Teulade-Fichou (2016 Jan 7)
Influence of the oxazole ring connection on the fluorescence of oxazoyl-triphenylamine biphotonic DNA probes.
Organic & biomolecular chemistry : 14 : 358-370 : DOI : 10.1039/c5ob02225h
Morel E., Poyer F., Vaslin L., Bombard S., Teulade-Fichou M.P. (2016 Jan 1)
Photoactivatable platinum(II) terpyridine derivatives for G-quadruplex DNA double anchoring
Inorganica Chimica Acta : 452 : 152-158 : DOI : 10.1016/j.ica.2016.02.033Année de publication : 2015
Matjaž Bončina, Črtomir Podlipnik, Ivo Piantanida, Julita Eilmes, Marie-Paule Teulade-Fichou, Gorazd Vesnaver, Jurij Lah (2015 Nov 8)
Thermodynamic fingerprints of ligand binding to human telomeric G-quadruplexes.
Nucleic acids research : 43 : 10376-86 : DOI : 10.1093/nar/gkv1167
Patrick Merle, Marine Gueugneau, Marie-Paule Teulade-Fichou, Mélanie Müller-Barthélémy, Simon Amiard, Emmanuel Chautard, Corinne Guetta, Véronique Dedieu, Yves Communal, Jean-Louis Mergny, Maria Gallego, Charles White, Pierre Verrelle, Andreï Tchirkov (2015 Nov 7)
Highly efficient radiosensitization of human glioblastoma and lung cancer cells by a G-quadruplex DNA binding compound.
Scientific reports : 5 : 16255 : DOI : 10.1038/srep16255
R Chennoufi, H Bougherara, N Gagey-Eilstein, B Dumat, E Henry, F Subra, F Mahuteau-Betzer, P Tauc, M-P Teulade-Fichou, E Deprez (2015 Oct 15)
Differential behaviour of cationic triphenylamine derivatives in fixed and living cells: triggering and imaging cell death.
Chemical communications (Cambridge, England) : 51 : 14881-14884 : DOI : 10.1039/c5cc05970d
Naoko Kotera, Florent Poyer, Anton Granzhan, Marie-Paule Teulade-Fichou (2015 Sep 18)
Efficient inhibition of human AP endonuclease 1 (APE1) via substrate masking by abasic site-binding macrocyclic ligands.
Chemical communications (Cambridge, England) : 51 : 15948-15951 : DOI : 10.1039/c5cc06084b
Guillaume Kellermann, Markus Kaiser, Florent Dingli, Olivier Lahuna, Delphine Naud-Martin, Florence Mahuteau-Betzer, Damarys Loew, Evelyne Ségal-Bendirdjian, Marie-Paule Teulade-Fichou, Sophie Bombard (2015 Sep 3)
Identification of human telomerase assembly inhibitors enabled by a novel method to produce hTERT.
Nucleic acids research : 43 : e99 : DOI : 10.1093/nar/gkv425
Xie X., Renvoise A., Granzhan A., Teulade-Fichou M.P. (2015 Jul 10)
Aggregating distyrylpyridinium dye as a bimodal structural probe for G-quadruplex DNA
New Journal of Chemistry : 39 : 5931-5935 : DOI : 10.1039/C5NJ01325A
Matjaž Bončina, Florian Hamon, Barira Islam, Marie-Paule Teulade-Fichou, Gorazd Vesnaver, Shozeb Haider, Jurij Lah (2015 Jun 16)
Dominant Driving Forces in Human Telomere Quadruplex Binding-Induced Structural Alterations.
Biophysical journal : 108 : 2903-2911 : DOI : 10.1016/j.bpj.2015.05.001
Aurèle Piazza, Michael Adrian, Frédéric Samazan, Brahim Heddi, Florian Hamon, Alexandre Serero, Judith Lopes, Marie-Paule Teulade-Fichou, Anh Tuân Phan, Alain Nicolas (2015 May 10)
Short loop length and high thermal stability determine genomic instability induced by G-quadruplex-forming minisatellites.
The EMBO journal : 34 : 1718-1734 : DOI : 10.15252/embj.201490702
Arivazhagan Rajendran, Masayuki Endo, Kumi Hidaka, Marie-Paule Teulade-Fichou, Jean-Louis Mergny, Hiroshi Sugiyama (2015 May 9)
Small molecule binding to a G-hairpin and a G-triplex: a new insight into anticancer drug design targeting G-rich regions.
Chemical communications (Cambridge, England) : 51 : 9181-9184 : DOI : 10.1039/c5cc01678a
Marko Trajkovski, Elodie Morel, Florian Hamon, Sophie Bombard, Marie-Paule Teulade-Fichou, Janez Plavec (2015 Apr 8)
Interactions of Pt-ttpy with G-Quadruplexes Originating from Promoter Region of the c-myc Gene Deciphered by NMR and Gel Electrophoresis Analysis.
Chemistry (Weinheim an der Bergstrasse, Germany) : 21 : 7798-807 : DOI : 10.1002/chem.201500347
Anne Cammas, Alexandre Dubrac, Benjamin Morel, Assala Lamaa, Christian Touriol, Marie-Paule Teulade-Fichou, Hervé Prats, Stefania Millevoi (2015 Apr 1)
Stabilization of the G-quadruplex at the VEGF IRES represses cap-independent translation.
RNA biology : 12 : 320-329 : DOI : 10.1080/15476286.2015.1017236
Adrien Marchand, Anton Granzhan, Keisuke Iida, Yamato Tsushima, Yue Ma, Kazuo Nagasawa, Marie-Paule Teulade-Fichou, Valérie Gabelica (2015 Jan 21)
Ligand-induced conformational changes with cation ejection upon binding to human telomeric DNA G-quadruplexes.
Journal of the American Chemical Society : 137 : 750-756 : DOI : 10.1021/ja5099403
Jana Novotna, Aurelien Laguerre, Anton Granzhan, Marc Pirrotta, Marie-Paule Teulade-Fichou, David Monchaud (2015 Jan 7)
Cationic azacryptands as selective three-way DNA junction binding agents.
Organic & biomolecular chemistry : 13 : 215-222 : DOI : 10.1039/c4ob01846jAnnée de publication : 2014
Laury Perriaud, Virginie Marcel, Charlotte Sagne, Vincent Favaudon, Aurore Guédin, Aurore De Rache, Corinne Guetta, Florian Hamon, Marie-Paule Teulade-Fichou, Pierre Hainaut, Jean-Louis Mergny, Janet Hall (2014 Oct 2)
Impact of G-quadruplex structures and intronic polymorphisms rs17878362 and rs1642785 on basal and ionizing radiation-induced expression of alternative p53 transcripts.
Carcinogenesis : 35 : 2706-2715 : DOI : 10.1093/carcin/bgu206
Fabien Hammerer, Guillaume Garcia, Pauline Charles, Aude Sourdon, Sylvain Achelle, Marie-Paule Teulade-Fichou, Philippe Maillard (2014 Jul 12)
Glycoconjugated porphyrin dimers as robust ratiometric temperature sensors.
Chemical communications (Cambridge, England) : 50 : 9529-9532 : DOI : 10.1039/c4cc03367a
Anton Granzhan, Naoko Kotera, Marie-Paule Teulade-Fichou (2014 Mar 17)
Finding needles in a basestack: recognition of mismatched base pairs in DNA by small molecules.
Chemical Society reviews : 43 : 3630-3665 : DOI : 10.1039/c3cs60455a
Delphine Naud-Martin, Xavier Martin-Benlloch, Florent Poyer, Florence Mahuteau-Betzer, Marie-Paule Teulade-Fichou (2014 Feb 1)
Acri-2,7-Py, a bright red-emitting DNA probe identified through screening of a distyryl dye library.
Biotechnology journal : 9 : 301-310 : DOI : 10.1002/biot.201300197
Chien-Hung Yu, Marie-Paule Teulade-Fichou, René C L Olsthoorn (2014 Feb 1)
Stimulation of ribosomal frameshifting by RNA G-quadruplex structures.
Nucleic acids research : 42 : 1887-1892 : DOI : 10.1093/nar/gkt1022
Daniela Verga, Florian Hamon, Florent Poyer, Sophie Bombard, Marie-Paule Teulade-Fichou (2014 Jan 20)
Photo-cross-linking probes for trapping G-quadruplex DNA.
Angewandte Chemie (International ed. in English) : 53 : 994-998 : DOI : 10.1002/anie.201307413
Wan Jun Chung, Brahim Heddi, Florian Hamon, Marie-Paule Teulade-Fichou, Anh Tuân Phan (2014 Jan 20)
Solution structure of a G-quadruplex bound to the bisquinolinium compound Phen-DC(3).
Angewandte Chemie (International ed. in English) : 53 : 999-1002 : DOI : 10.1002/anie.201308063
Fabien Hammerer, Guillaume Garcia, Su Chen, Florent Poyer, Sylvain Achelle, Céline Fiorini-Debuisschert, Marie-Paule Teulade-Fichou, Philippe Maillard (2014 Jan 18)
Synthesis and characterization of glycoconjugated porphyrin triphenylamine hybrids for targeted two-photon photodynamic therapy.
The Journal of organic chemistry : 79 : 1406-17 : DOI : 10.1021/jo402658h
Rajendran A., Endo M., Hidaka K., Thao Tran P.L., Teulade-Fichou M.P., Mergny J.L., Sugiyama H. (2014 Jan 1)
G-quadruplex-binding ligand-induced DNA synapsis inside a DNA origami frame
RSC Adv. : 4 : 6346-6355 : DOI : 10.1039/C3RA45676EAnnée de publication : 2013
Hélène Bertrand, Régis Guillot, Marie-Paule Teulade-Fichou, Denis Fichou (2013 Sep 13)
Synthesis, properties, and remarkable 2 D Self-Assembly at the Liquid/Solid interface of a series of triskele-shaped 5,11,17-triazatrinaphthylenes (TrisK).
Chemistry A European Journal : 19 : 14654-14664 : DOI : 10.1002/chem.201300705
Blaise Dumat, Guillaume Bordeau, Elodie Faurel-Paul, Florence Mahuteau-Betzer, Nicolas Saettel, Germain Metge, Céline Fiorini-Debuisschert, Fabrice Charra, Marie-Paule Teulade-Fichou (2013 Aug 20)
DNA switches on the two-photon efficiency of an ultrabright triphenylamine fluorescent probe specific of AT regions.
Journal of the American Chemical Society : 135 : 12697-12706 : DOI : 10.1021/ja404422z
Sanjay Kumar Bharti, Joshua A Sommers, Fourbears George, Jochen Kuper, Florian Hamon, Kazuo Shin-ya, Marie-Paule Teulade-Fichou, Caroline Kisker, Robert M Brosh (2013 Aug 13)
Specialization among iron-sulfur cluster helicases to resolve G-quadruplex DNA structures that threaten genomic stability.
The Journal of biological chemistry : 288 : 28217-28229 : DOI : 10.1074/jbc.M113.496463
Xiao Xie, Bina Choi, Eric Largy, Régis Guillot, Anton Granzhan, Marie-Paule Teulade-Fichou (2013 Jan 8)
Asymmetric distyrylpyridinium dyes as red-emitting fluorescent probes for quadruplex DNA.
Chemistry A European Journal : 19 : 1214-1226 : DOI : 10.1002/chem.201203710
Guillaume Garcia, Fabien Hammerer, Florent Poyer, Sylvain Achelle, Marie-Paule Teulade-Fichou, Philippe Maillard (2013 Jan 1)
Carbohydrate-conjugated porphyrin dimers: synthesis and photobiological evaluation for a potential application in one-photon and two-photon photodynamic therapy.
Bioorganic & medicinal chemistry : 21 : 153-65 : DOI : 10.1016/j.bmc.2012.10.042Année de publication : 2012
Assitan Sidibe, Florian Hamon, Eric Largy, Dennis Gomez, Marie-Paule Teulade-Fichou, Chantal Trentesaux, Jean-François Riou (2012 Dec 1)
Effects of a halogenated G-quadruplex ligand from the pyridine dicarboxamide series on the terminal sequence of XpYp telomere in HT1080 cells.
Biochimie : 94 : 2559-2568 : DOI : 10.1016/j.biochi.2012.07.003
Michele Petenzi, Daniela Verga, Eric Largy, Florian Hamon, Filippo Doria, Marie-Paule Teulade-Fichou, Aurore Guédin, Jean-Louis Mergny, Mariella Mella, Mauro Freccero (2012 Sep 22)
Cationic pentaheteroaryls as selective G-quadruplex ligands by solvent-free microwave-assisted synthesis.
Chemistry A European Journal : 18 : 14487-14496 : DOI : 10.1002/chem.201202097
Eric Largy, Anton Granzhan, Florian Hamon, Daniela Verga, Marie-Paule Teulade-Fichou (2012 Aug 14)
Visualizing the quadruplex: from fluorescent ligands to light-up probes.
Topics in current chemistry : 330 : 111-77 : DOI : 10.1007/128_2012_346
Muriel Jourdan, Anton Granzhan, Regis Guillot, Pascal Dumy, Marie-Paule Teulade-Fichou (2012 Jun 1)
Double threading through DNA: NMR structural study of a bis-naphthalene macrocycle bound to a thymine-thymine mismatch.
Nucleic Acids Research : 40 : 5115-5128 : DOI : 10.1093/nar/gks067
Blaise Dumat, Guillaume Bordeau, Ana I Aranda, Florence Mahuteau-Betzer, Yara El Harfouch, Germain Metgé, Fabrice Charra, Céline Fiorini-Debuisschert, Marie-Paule Teulade-Fichou (2012 May 23)
Vinyl-triphenylamine dyes, a new family of switchable fluorescent probes for targeted two-photon cellular imaging: from DNA to protein labeling.
Organic & biomolecular chemistry : 30 : 6054-6061 : DOI : 10.1039/c2ob25515d
Eric Largy, Florian Hamon, Marie-Paule Teulade-Fichou (2012 May 1)
A streptavidin paramagnetic-particle based competition assay for the evaluation of the optical selectivity of quadruplex nucleic acid fluorescent probes.
Methods (San Diego, Calif.) : 57 : 129-137 : DOI : 10.1016/j.ymeth.2012.02.008
Rashi Halder, Jean-Francois Riou, Marie-Paule Teulade-Fichou, Tancred Frickey, Jörg S Hartig (2012 Mar 13)
Bisquinolinium compounds induce quadruplex-specific transcriptome changes in HeLa S3 cell lines.
BMC research notes : 5 : 138 : DOI : 10.1186/1756-0500-5-138
Eric Largy, Nicolas Saettel, Florian Hamon, Sylvie Dubruille, Marie-Paule Teulade-Fichou (2012 Mar 2)
Screening of a chemical library by HT-G4-FID for discovery of selective G-quadruplex binders.
Current pharmaceutical design : 18 : 1992-2001 : DOI : 10.2174/138161212799958350Année de publication : 2011
Eric Largy, Florian Hamon, Frédéric Rosu, Valérie Gabelica, Edwin De Pauw, Aurore Guédin, Jean-Louis Mergny, Marie-Paule Teulade-Fichou (2011 Nov 18)
Tridentate N-donor palladium(II) complexes as efficient coordinating quadruplex DNA binders.
Chemistry (Weinheim an der Bergstrasse, Germany) : 17 : 13274-13283 : DOI : 10.1002/chem.201102300
Patrick Merle, Bertrand Evrard, Anne Petitjean, Jean-Marie Lehn, Marie-Paule Teulade-Fichou, Emmanuel Chautard, Anne De Cian, Lionel Guittat, Phong Lan Thao Tran, Jean-Louis Mergny, Pierre Verrelle, Andreï Tchirkov (2011 Oct 12)
Telomere targeting with a new G4 ligand enhances radiation-induced killing of human glioblastoma cells.
Molecular cancer therapeutics : 10 : 1784-1795 : DOI : 10.1158/1535-7163.MCT-10-0664
Hélène Bertrand, Fabien Silly, Marie-Paule Teulade-Fichou, Ludovic Tortech, Denis Fichou (2011 Aug 11)
Locking the free-rotation of a prochiral star-shaped guest molecule inside a two-dimensional nanoporous network by introduction of chlorine atoms
Chemical communications (Cambridge, England) : 36 : 10091-10093 : DOI : 10.1039/c1cc12951a
Phong Lan Thao Tran, Eric Largy, Florian Hamon, Marie-Paule Teulade-Fichou, Jean-Louis Mergny (2011 Aug 2)
Fluorescence intercalator displacement assay for screening G4 ligands towards a variety of G-quadruplex structures.
Biochimie : 93 : 1288-1296 : DOI : 10.1016/j.biochi.2011.05.011
Hamon F., Largy E., Guédin-Beaurepaire A., Rouchon-Dagois M., Sidibe A., Monchaud D., Mergny J.L., Riou J.F., Nguyen C.H., Teulade-Fichou M.P. (2011 Aug 2)
An acyclic oligoheteroaryle that discriminates strongly between diverse G-quadruplex topologies.
Angewandte Chemie (International ed. in English) : 50 : 8745-8749 : DOI : 10.1002/anie.201103422
Amandine Renaud de la Faverie, Florian Hamon, Carmelo Di Primo, Eric Largy, Eric Dausse, Laurence Delaurière, Corinne Landras-Guetta, Jean-Jacques Toulmé, Marie-Paule Teulade-Fichou, Jean-Louis Mergny (2011 Aug 1)
Nucleic acids targeted to drugs: SELEX against a quadruplex ligand.
Biochimie : 93 : 1357-1367 : DOI : 10.1016/j.biochi.2011.05.022
Judith Lopes, Aurèle Piazza, Rodrigo Bermejo, Barry Kriegsman, Arianna Colosio, Marie-Paule Teulade-Fichou, Marco Foiani, Alain Nicolas (2011 Jun 28)
G-quadruplex-induced instability during leading-strand replication.
The EMBO journal : 30 : 4033-4046 : DOI : 10.1038/emboj.2011.316
Kangkan Halder, Eric Largy, Martin Benzler, Marie-Paule Teulade-Fichou, Jörg S Hartig (2011 Jun 18)
Efficient suppression of gene expression by targeting 5′-UTR-based RNA quadruplexes with bisquinolinium compounds.
Chembiochem : a European journal of chemical biology : 12 : 1663-1668 : DOI : 10.1002/cbic.201100228
B Dumat, G Bordeau, E Faurel-Paul, F Mahuteau-Betzer, N Saettel, M Bombled, G Metgé, F Charra, C Fiorini-Debuisschert, M-P Teulade-Fichou (2011 Jun 16)
N-phenyl-carbazole-based two-photon fluorescent probes: strong sequence dependence of the duplex vs quadruplex selectivity.
Biochimie : 93 : 1209-1218 : DOI : 10.1016/j.biochi.2011.05.035
Fabien Hammerer, Sylvain Achelle, Patrice Baldeck, Philippe Maillard, Marie-Paule Teulade-Fichou (2011 May 19)
Influence of carbohydrate biological vectors on the two-photon resonance of porphyrin oligomers.
The journal of physical chemistry. A : 115 : 6503-6508 : DOI : 10.1021/jp202436x
Eric Largy, Florian Hamon, Marie-Paule Teulade-Fichou (2011 Apr 30)
Development of a high-throughput G4-FID assay for screening and evaluation of small molecules binding quadruplex nucleic acid structures.
Analytical and bioanalytical chemistry : 400 : 3419-3427 : DOI : 10.1007/s00216-011-5018-z
Hélène Bertrand, Anton Granzhan, David Monchaud, Nicolas Saettel, Régis Guillot, Sarah Clifford, Aurore Guédin, Jean-Louis Mergny, Marie-Paule Teulade-Fichou (2011 Apr 11)
Recognition of G-quadruplex DNA by triangular star-shaped compounds: with or without side chains?
Chemistry (Weinheim an der Bergstrasse, Germany) : 17 : 4529-4539 : DOI : 10.1002/chem.201002810
Jasmine S Smith, Qijun Chen, Liliya A Yatsunyk, John M Nicoludis, Mark S Garcia, Ramon Kranaster, Shankar Balasubramanian, David Monchaud, Marie-Paule Teulade-Fichou, Lara Abramowitz, David C Schultz, F Brad Johnson (2011 Mar 13)
Rudimentary G-quadruplex-based telomere capping in Saccharomyces cerevisiae.
Nature structural & molecular biology : 18 : 478-485 : DOI : 10.1038/nsmb.2033
Virginie Marcel, Phong L T Tran, Charlotte Sagne, Ghyslaine Martel-Planche, Laurence Vaslin, Marie-Paule Teulade-Fichou, Janet Hall, Jean-Louis Mergny, Pierre Hainaut, Eric Van Dyck (2011 Mar 1)
G-quadruplex structures in TP53 intron 3: role in alternative splicing and in production of p53 mRNA isoforms.
Carcinogenesis : 32 : 271-278 : DOI : 10.1093/carcin/bgq253Année de publication : 2010
Dennis Gomez, Aurore Guédin, Jean-Louis Mergny, Bernard Salles, Jean-François Riou, Marie-Paule Teulade-Fichou, Patrick Calsou (2010 Nov 1)
A G-quadruplex structure within the 5′-UTR of TRF2 mRNA represses translation in human cells.
Nucleic acids research : 38 : 7187-7198 : DOI : 10.1093/nar/gkq563
David Monchaud, Anton Granzhan, Nicolas Saettel, Aurore Guédin, Jean-Louis Mergny, Marie-Paule Teulade-Fichou (2010 Aug 21)
« One ring to bind them all »-part I: the efficiency of the macrocyclic scaffold for g-quadruplex DNA recognition.
Journal of nucleic acids : 2010 : ID 525862 : DOI : 10.4061/2010/525862
Anton Granzhan, David Monchaud, Nicolas Saettel, Aurore Guédin, Jean-Louis Mergny, Marie-Paule Teulade-Fichou (2010 Aug 21)
« One Ring to Bind Them All »-Part II: Identification of Promising G-Quadruplex Ligands by Screening of Cyclophane-Type Macrocycles.
Journal of nucleic acids : 2010 : ID 460561 : DOI : 10.4061/2010/460561
Aurèle Piazza, Jean-Baptiste Boulé, Judith Lopes, Katie Mingo, Eric Largy, Marie-Paule Teulade-Fichou, Alain Nicolas (2010 Jul 1)
Genetic instability triggered by G-quadruplex interacting Phen-DC compounds in Saccharomyces cerevisiae.
Nucleic acids research : 38 : 4337-4348 : DOI : 10.1093/nar/gkq136
Pierre Murat, Romaric Bonnet, Angéline Van der Heyden, Nicolas Spinelli, Pierre Labbé, David Monchaud, Marie-Paule Teulade-Fichou, Pascal Dumy, Eric Defrancq (2010 May 25)
Template-assembled synthetic G-quadruplex (TASQ): a useful system for investigating the interactions of ligands with constrained quadruplex topologies.
Chemistry (Weinheim an der Bergstrasse, Germany) : 16 : 6106-6114 : DOI : 10.1002/chem.200903456
Anton Granzhan, Eric Largy, Nicolas Saettel, Marie-Paule Teulade-Fichou (2010 Jan 18)
Macrocyclic DNA-mismatch-binding ligands: structural determinants of selectivity.
Chemistry (Weinheim an der Bergstrasse, Germany) : 16 : 878-889 : DOI : 10.1002/chem.200901989Année de publication : 2009
Julien Debray, Walid Zeghida, Muriel Jourdan, David Monchaud, Marie-Louise Dheu-Andries, Pascal Dumy, Marie-Paule Teulade-Fichou, Martine Demeunynck (2009 Dec 21)
Synthesis and evaluation of fused bispyrimidinoacridines as novel pentacyclic analogues of quadruplex-binder BRACO-19.
Organic & biomolecular chemistry : 7 : 5219-5228 : DOI : 10.1039/b912716j
David Monchaud, Marie-Paule Teulade-Fichou (2009 Dec 17)
G4-FID: a fluorescent DNA probe displacement assay for rapid evaluation of quadruplex ligands.
Methods in molecular biology (Clifton, N.J.)G-Quadruplex DNA : 257-271 : DOI : 10.1007/978-1-59745-363-9_15
Nicolas Smargiasso, Valérie Gabelica, Christian Damblon, Frédéric Rosu, Edwin De Pauw, Marie-Paule Teulade-Fichou, J Alexandra Rowe, Antoine Claessens (2009 Aug 6)
Putative DNA G-quadruplex formation within the promoters of Plasmodium falciparum var genes.
BMC genomics : 10 : 362 : DOI : 10.1186/1471-2164-10-362
Hélène Bertrand, Sophie Bombard, David Monchaud, Eric Talbot, Aurore Guédin, Jean-Louis Mergny, Renate Grünert, Patrick J Bednarski, Marie-Paule Teulade-Fichou (2009 Jul 21)
Exclusive platination of loop adenines in the human telomeric G-quadruplex.
Organic & biomolecular chemistry : 7 : 2864-2871 : DOI : 10.1039/b904599f
Peng Yang, Anne De Cian, Marie-Paule Teulade-Fichou, Jean-Louis Mergny, David Monchaud (2009 Mar 9)
Engineering bisquinolinium/thiazole orange conjugates for fluorescent sensing of G-quadruplex DNA.
Angewandte Chemie (International ed. in English) : 48 : 2188-2191 : DOI : 10.1002/anie.200805613
Anton Granzhan, Marie-Paule Teulade-Fichou (2009 Jan 26)
A fluorescent bisanthracene macrocycle discriminates between matched and mismatch-containing DNA.
Chemistry (Weinheim an der Bergstrasse, Germany) : 15 : 1314-1318 : DOI : 10.1002/chem.200802421Année de publication : 2008
Guillaume Bordeau, Rémy Lartia, Germain Metge, Céline Fiorini-Debuisschert, Fabrice Charra, Marie-Paule Teulade-Fichou (2008 Nov 19)
Trinaphthylamines as robust organic materials for two-photon-induced fluorescence.
Journal of the American Chemical Society : 130 : 16836-16837 : DOI : 10.1021/ja8055112
Anne De Cian, Philippe Grellier, Elisabeth Mouray, Delphine Depoix, Hélène Bertrand, David Monchaud, Marie-Paule Teulade-Fichou, Jean-Louis Mergny, Patrizia Alberti (2008 Nov 3)
Plasmodium telomeric sequences: structure, stability and quadruplex targeting by small compounds.
Chembiochem : a European journal of chemical biology : 9 : 2730-2739 : DOI : 10.1002/cbic.200800330
Anja Henn, Astrid Joachimi, Diana P N Gonçalves, David Monchaud, Marie-Paule Teulade-Fichou, Jeremy K M Sanders, Jörg S Hartig (2008 Nov 3)
Inhibition of dicing of guanosine-rich shRNAs by quadruplex-binding compounds.
Chembiochem : a European journal of chemical biology : 9 : 2722-2729 : DOI : 10.1002/cbic.200800271
Hélène Bertrand, Sophie Bombard, David Monchaud, Marie-Paule Teulade-Fichou (2008 Sep 1)
New platinum(II) complexes targeting the loops of the human telomeric G-quadruplex.
Nucleic acids symposium series (2004) : 52 : 163-164 : DOI : 10.1093/nass/nrn083
G Bordeau, E Faurel, C Allain, R Lartia, F Schmidt, C Fiorini-Debuisschert, F Charra, G Metge, P Tauc, M-P Teulade-Fichou (2008 Sep 1)
New triarylamine-based far-red DNA stainers with high two-photon absorption properties.
Nucleic acids symposium series (2004) : 52 : 155-156 : DOI : 10.1093/nass/nrn079
Matthias Bahr, Valerie Gabélica, Anton Granzhan, Elmar Weinhold, Marie-Paule Teulade-Fichou (2008 Sep 1)
Recognition of homopyrimidine mismatches by distance-constrained macrocyclic bisintercalators.
Nucleic acids symposium series (2004) : 52 : 109-110 : DOI : 10.1093/nass/nrn056
Matthias Bahr, Valérie Gabelica, Anton Granzhan, Marie-Paule Teulade-Fichou, Elmar Weinhold (2008 Sep 1)
Selective recognition of pyrimidine-pyrimidine DNA mismatches by distance-constrained macrocyclic bis-intercalators.
Nucleic acids research : 36 : 5000-5012 : DOI : 10.1093/nar/gkn392
D Monchaud, C Allain, H Bertrand, N Smargiasso, F Rosu, V Gabelica, A De Cian, J-L Mergny, M-P Teulade-Fichou (2008 Aug 1)
Ligands playing musical chairs with G-quadruplex DNA: a rapid and simple displacement assay for identifying selective G-quadruplex binders.
Biochimie : 90 : 1207-1223 : DOI : 10.1016/j.biochi.2008.02.019
David Monchaud, Peng Yang, Laurent Lacroix, Marie-Paule Teulade-Fichou, Jean-Louis Mergny (2008 Jun 16)
A metal-mediated conformational switch controls G-quadruplex binding affinity.
Angewandte Chemie (International ed. in English) : 47 : 4858-4861 : DOI : 10.1002/anie.200800468
Samir Amrane, Anne De Cian, Frédéric Rosu, Markus Kaiser, Edwin De Pauw, Marie-Paule Teulade-Fichou, Jean-Louis Mergny (2008 May 23)
Identification of trinucleotide repeat ligands with a FRET melting assay.
Chembiochem : a European journal of chemical biology : 9 : 1229-1234 : DOI : 10.1002/cbic.200800062
David Monchaud, Marie-Paule Teulade-Fichou (2008 Feb 21)
A hitchhiker’s guide to G-quadruplex ligands.
Organic & biomolecular chemistry : 6 : 627-636 : DOI : 10.1039/b714772b
Rémy Lartia, Clémence Allain, Guillaume Bordeau, Falk Schmidt, Céline Fiorini-Debuisschert, Fabrice Charra, Marie-Paule Teulade-Fichou (2008 Feb 2)
Synthetic strategies to derivatizable triphenylamines displaying high two-photon absorption.
The Journal of organic chemistry : 73 : 1732-1744 : DOI : 10.1021/jo702002y
Falk H-G Schmidt, Michael Hüben, Basar Gider, François Renault, Marie-Paule Teulade-Fichou, Elmar Weinhold (2008 Jan 1)
Sequence-specific Methyltransferase-Induced Labelling (SMILing) of plasmid DNA for studying cell transfection.
Bioorganic & medicinal chemistry : 16 : 40-48 : DOI : 10.1016/j.bmc.2007.04.054Année de publication : 2007
D Monchaud, C Allain, M-P Teulade-Fichou (2007 Dec 11)
Thiazole orange: a useful probe for fluorescence sensing of G-quadruplex-ligand interactions.
Nucleosides, nucleotides & nucleic acids : 26 : 1585-1588 : DOI : 10.1080/15257770701548212
Anne De Cian, Gael Cristofari, Patrick Reichenbach, Elsa De Lemos, David Monchaud, Marie-Paule Teulade-Fichou, Kazuo Shin-Ya, Laurent Lacroix, Joachim Lingner, Jean-Louis Mergny (2007 Oct 30)
Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action.
Proceedings of the National Academy of Sciences of the United States of America : 100 : 17347-17352 : DOI : 10.1073/pnas.0707365104
Hélène Bertrand, David Monchaud, Anne De Cian, Régis Guillot, Jean-Louis Mergny, Marie-Paule Teulade-Fichou (2007 Aug 21)
The importance of metal geometry in the recognition of G-quadruplex-DNA by metal-terpyridine complexes.
Organic & biomolecular chemistry : 5 : 2555-2559 : DOI : 10.1039/B708635K
Hélène Bertrand, Sophie Bombard, David Monchaud, Marie-Paule Teulade-Fichou (2007 Jul 20)
A platinum-quinacridine hybrid as a G-quadruplex ligand.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry : 12 : 1003-14 : DOI : 10.1007/s00775-007-0273-3
Anne De Cian, Lionel Guittat, Markus Kaiser, Barbara Saccà, Samir Amrane, Anne Bourdoncle, Patrizia Alberti, Marie-Paule Teulade-Fichou, Laurent Lacroix, Jean-Louis Mergny (2007 Jun 1)
Fluorescence-based melting assays for studying quadruplex ligands.
Methods (San Diego, Calif.) : 42 : 183-195 : DOI : 10.1016/j.ymeth.2006.10.004
Candide Hounsou, Lionel Guittat, David Monchaud, Muriel Jourdan, Nicolas Saettel, Jean-Louis Mergny, Marie-Paule Teulade-Fichou (2007 May 14)
G-quadruplex recognition by quinacridines: a SAR, NMR, and biological study.
ChemMedChem : 2 : 655-666
Clémence Allain, Falk Schmidt, Rémy Lartia, Guillaume Bordeau, Céline Fiorini-Debuisschert, Fabrice Charra, Patrick Tauc, Marie-Paule Teulade-Fichou (2007 Mar 5)
Vinyl-pyridinium triphenylamines: novel far-red emitters with high photostability and two-photon absorption properties for staining DNA.
Chembiochem : a European journal of chemical biology : 8 : 424-433 : DOI : 10.1002/cbic.200600483
Valérie Gabelica, Erin Shammel Baker, Marie-Paule Teulade-Fichou, Edwin De Pauw, Michael T Bowers (2007 Jan 31)
Stabilization and structure of telomeric and c-myc region intramolecular G-quadruplexes: the role of central cations and small planar ligands.
Journal of the American Chemical Society : 129 : 895-904 : DOI : 10.1021/ja065989p
Anne De Cian, Elsa Delemos, Jean-Louis Mergny, Marie-Paule Teulade-Fichou, David Monchaud (2007 Jan 30)
Highly efficient G-quadruplex recognition by bisquinolinium compounds.
Journal of the American Chemical Society : 129 : 1856-1857 : DOI : 10.1021/ja067352bAnnée de publication : 2006
David Monchaud, Clémence Allain, Marie-Paule Teulade-Fichou (2006 Sep 15)
Development of a fluorescent intercalator displacement assay (G4-FID) for establishing quadruplex-DNA affinity and selectivity of putative ligands.
Bioorganic & medicinal chemistry letters : 16 : 4842-4845 : DOI : 10.1016/j.bmcl.2006.06.067
Clémence Allain, David Monchaud, Marie-Paule Teulade-Fichou (2006 Sep 7)
FRET templated by G-quadruplex DNA: a specific ternary interaction using an original pair of donor/acceptor partners.
Journal of the American Chemical Society : 128 : 11890-11893 : DOI : 10.1021/ja062193h
Markus Kaiser, Anne De Cian, Matthieu Sainlos, Christian Renner, Jean-Louis Mergny, Marie-Paule Teulade-Fichou (2006 Mar 10)
Neomycin-capped aromatic platforms: quadruplex DNA recognition and telomerase inhibition.
Organic & biomolecular chemistry : 4 : 1049-1057 : DOI : 10.1039/b516378a
Markus Kaiser, Matthieu Sainlos, Jean-Marie Lehn, Sophie Bombard, Marie-Paule Teulade-Fichou (2006 Jan 13)
Aminoglycoside-quinacridine conjugates: towards recognition of the P6.1 element of telomerase RNA.
Chembiochem : a European journal of chemical biology : 7 : 321-329 : DOI : 10.1002/cbic.200500354Année de publication : 2003
Arnaud David, Nathalie Bleimling, Christine Beuck, Jean-Marie Lehn, Elmar Weinhold, Marie-Paule Teulade-Fichou (2003 Dec 9)
DNA mismatch-specific base flipping by a bisacridine macrocycle.
Chembiochem : a European journal of chemical biology : 4 : 1326-1331 : DOI : 10.1002/cbic.200300693
M P Teulade-Fichou, C Hounsou, L Guittat, J L Mergny, P Alberti, C Carrasco, C Bailly, J M Lehn, W D Wilson (2003 Oct 21)
Molecular recognition of quadruplex DNA by quinacridine derivatives.
Nucleosides, nucleotides & nucleic acids : 1483-1485 : DOI : 10.1081/NCN-120023016
Marie-Paule Teulade-Fichou, Carolina Carrasco, Lionel Guittat, Christian Bailly, Patrizia Alberti, Jean-Louis Mergny, Arnaud David, Jean-Marie Lehn, W David Wilson (2003 Apr 17)
Selective recognition of G-Quadruplex telomeric DNA by a bis(quinacridine) macrocycle.
Journal of the American Chemical Society : 125 : 4732-4740 : DOI : 10.1021/ja021299jAnnée de publication : 2002
Sébastien Lyonnais, Candide Hounsou, Marie-Paule Teulade-Fichou, Josette Jeusset, Eric Le Cam, Gilles Mirambeau (2002 Dec 6)
G-quartets assembly within a G-rich DNA flap. A possible event at the center of the HIV-1 genome.
Nucleic acids research : 30 : 5276-5283 : DOI : 10.1093/nar/gkf644
Jean-Louis Mergny, Jean-François Riou, Patrick Mailliet, Marie-Paule Teulade-Fichou, Eric Gilson (2002 Feb 14)
Natural and pharmacological regulation of telomerase.
Nucleic acids research : 30 : 839-865 : DOI : 10.1093/nar/30.4.839
P Alberti, J Ren, M P Teulade-Fichou, L Guittat, J F Riou, J Chaires, C Hélène, J P Vigneron, J M Lehn, J L Mergny (2002 Jan 16)
Interaction of an acridine dimer with DNA quadruplex structures.
Journal of biomolecular structure & dynamics : 19 : 505-513 : DOI : 10.1080/07391102.2001.10506758Année de publication : 2001
M P Teulade-Fichou, D Perrin, A Boutorine, D Polverari, J P Vigneron, J M Lehn, J S Sun, T Garestier, C Helene (2001 Sep 20)
Direct photocleavage of HIV-DNA by quinacridine derivatives triggered by triplex formation.
Journal of the American Chemical Society : 123 : 9283-9292 : DOI : 10.1021/ja0109040
J L Mergny, L Lacroix, M P Teulade-Fichou, C Hounsou, L Guittat, M Hoarau, P B Arimondo, J P Vigneron, J M Lehn, J F Riou, T Garestier, C Hélène (2001 Mar 15)
Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay.
Proceedings of the National Academy of Sciences of the United States of America : 98 : 3062-3067 : DOI : 10.1073/pnas.051620698Année de publication : 2000
M P Teulade-Fichou, M Fauquet, O Baudoin, J P Vigneron, J M Lehn (2000 Jan 1)
DNA double helix destabilizing properties of cyclobisintercaland compounds and competition with a single strand binding protein.
Bioorganic & medicinal chemistry : 8 : 215-222 : DOI : 10.1016/s0968-0896(99)00283-7Année de publication : 1999
M Jourdan, J Garcia, J Lhomme, M P Teulade-Fichou, J P Vigneron, J M Lehn (1999 Nov 26)
Threading bis-intercalation of a macrocyclic bisacridine at abasic sites in DNA: nuclear magnetic resonance and molecular modeling study.
Biochemistry : 38 : 14205-14213 : DOI : 10.1021/bi991111hAnnée de publication : 1998
A J Blacker, M P Teulade-Fichou, J P Vigneron, M Fauquet, J M Lehn (1998 Mar 17)
Selective photocleavage of single-stranded nucleic acids by cyclobisintercaland molecules.
Bioorganic & medicinal chemistry letters : 8 : 601-606 : DOI : 10.1016/s0960-894x(98)00085-7Année de publication : 1997
A Slama-Schwok, F Peronnet, E Hantz-Brachet, E Taillandier, M P Teulade-Fichou, J P Vigneron, M Best-Belpomme, J M Lehn (1997 Jul 1)
