Sondes de structures et sondes photoactivables pour les acides nucléique et les kinases

Membres de l’équipe

Florence Mahuteau-Betzer

florence_mahuteau-betzer

Florence Mahuteau-Betzer Equipe Teulade-Fichou Directeur adjoint d'unité Responsable scientifique Chargée de recherche CNRS Tél : Retour à la liste

Publications clés

Année de publication : 2018

Luis M.G. Abegão, Ruben D Fonseca, Tárcius N Ramos, Florence Mahuteau-Betzer, Sandrine PIGUEL, José J. Rodrigues Jr, Cleber R. Mendonca, Sylvio Canuto, Daniel Luis Silva, and Leonardo De Boni (2018 Apr 12)

Oxazole dyes with potential for photoluminescence bioprobes: A two-Photon absorption study

The Journal of Physical Chemistry C : 122 : 10526-10534 : DOI : 10.1021/acs.jpcc.8b01904
Hammerer F., Poyer F., Fourmois L., Chen S., Garcia G., Teulade-Fichou M.P., Maillard P., Mahuteau-Betzer F. (2018 Jan 1)

Mitochondria-targeted cationic porphyrin-triphenylamine hybrids for enhanced two-photon photodynamic therapy

Bioorganic & Medicinal Chemistry : 26 : 107-118 : DOI : 10.1016/j.bmc.2017.11.024

Année de publication : 2017

Pauline Gilson, Fernando Josa-Prado, Claire Beauvineau, Delphine Naud-Martin, Laetitia Vanwonterghem, Florence Mahuteau-Betzer, Alexis Moreno, Pierre Falson, Laurence Lafanechère, Véronique Frachet, Jean-Luc Coll, Jose Fernando Díaz, Amandine Hurbin, Benoit Busser (2017 Sep 2)

Identification of pyrrolopyrimidine derivative PP-13 as a novel microtubule-destabilizing agent with promising anticancer properties.

Scientific reports : 10209 : DOI : 10.1038/s41598-017-09491-9
Claire Beauvineau, Corinne Guetta, Marie-Paule Teulade-Fichou, Florence Mahuteau-Betzer (2017 Aug 14)

PhenDV, a turn-off fluorescent quadruplex DNA probe for improving the sensitivity of drug screening assays

Organic & Biomolecular Chemistry : 15 : 7117-7121 : DOI : 10.1039/c7ob01705g
Marie-Paule Teulade-Fichou, Joël Lefebvre, Corinne Guetta, Florent Poyer, Florence Mahuteau-Betzer (2017 Jul 13)

Copper-alkyne complexation is responsible for the Nucleolar Localisation of Quadruplex Nucleic Acid Drugs Labelled by Click Chemistry.

Angewandte Chemie (International ed. in English) : 56 : 11365-11369 : DOI : 10.1002/anie.201703783
Chennoufi R., Mahuteau-Betzer F., Tauc P., Teulade-Fichou M.P., Deprez E. (2017 Jun 18)

Triphenylamines Induce Cell Death Upon 2-Photon Excitation

MOLECULAR IMAGING : 16 : DOI : 10.1177/1536012117714164
Morgan Pellerano, Sergey Tcherniuk, Corine Perals, Thi Nhu Ngoc Van, Elsa Garcin, Florence Mahuteau-Betzer, Marie-Paule Teulade-Fichou, May C Morris (2017 Apr 22)

Targeting Conformational Activation of CDK2 Kinase.

Biotechnology journal : 12 : 1600531 : DOI : 10.1002/biot.201600531
Gilles Galvani, K Harsha Vardhan Reddy, Claire Beauvineau, NourEddine Ghermani, Florence Mahuteau-Betzer, Mouad Alami, Samir Messaoudi (2017 Feb 17)

Conversion of 3-Bromo-2H-coumarins to 3-(Benzofuran-2-yl)-2H-coumarins under Palladium Catalysis: Synthesis and Photophysical Properties Study.

Organic letters : 19 : 910-913 : DOI : 10.1021/acs.orglett.7b00069
J Santo, C Lopez-Herrera, C Apolit, Y Bareche, L Lapasset, C Chavey, S Capozi, F Mahuteau-Betzer, R Najman, P Fornarelli, I C Lopez-Mejía, G Béranger, F Casas, E-Z Amri, B Pau, D Scherrer, J Tazi (2017 Feb 14)

Pharmacological modulation of LMNA SRSF1-dependent splicing abrogates diet-induced obesity in mice.

International journal of obesity : 41 : 390-401 : DOI : 10.1038/ijo.2016.220

Année de publication : 2016

Morgan Pellerano, Delphine Naud-Martin, Marion Peyressatre, Camille Prével, Marie-Paule Teulade-Fichou, May Morris, Florence Mahuteau-Betzer (2016 Mar 17)

TP-2Rho Is a Sensitive Solvatochromic Red-Shifted Probe for Monitoring the Interactions between CDK4 and Cyclin D.

Chembiochem : a European journal of chemical biology : 17 : 737-44 : DOI : 10.1002/cbic.201500641
Rahima Chennoufi, Houcine Bougherara, Nathalie Gagey-Eilstein, Blaise Dumat, Etienne Henry, Frédéric Subra, Stéphanie Bury-Moné, Florence Mahuteau-Betzer, Patrick Tauc, Marie-Paule Teulade-Fichou, Eric Deprez (2016 Mar 8)

Mitochondria-targeted Triphenylamine Derivatives Activatable by Two-Photon Excitation for Triggering and Imaging Cell Apoptosis.

Scientific reports : 6 : 21458 : DOI : 10.1038/srep21458

Année de publication : 2015

Blaise Dumat, Elodie Faurel-Paul, Pauline Fornarelli, Nicolas Saettel, Germain Metgé, Céline Fiorini-Debuisschert, Fabrice Charra, Florence Mahuteau-Betzer, Marie-Paule Teulade-Fichou (2015 Nov 25)

Influence of the oxazole ring connection on the fluorescence of oxazoyl-triphenylamine biphotonic DNA probes.

Organic & biomolecular chemistry : 14 : 358-370 : DOI : 10.1039/c5ob02225h
R Chennoufi, H Bougherara, N Gagey-Eilstein, B Dumat, E Henry, F Subra, F Mahuteau-Betzer, P Tauc, M-P Teulade-Fichou, E Deprez (2015 Aug 26)

Differential behaviour of cationic triphenylamine derivatives in fixed and living cells: triggering and imaging cell death.

Chemical communications (Cambridge, England) : 80 : 14881-14884 : DOI : 10.1039/c5cc05970d
Kathleen Solmont, Hamza Boufroura, Amel Souibgui, Pauline Fornarelli, Anne Gaucher, Florence Mahuteau-Betzer, Béchir Ben Hassine, Damien Prim (2015 May 13)

Divergent strategy for the synthesis of original dihydrobenzo- and dihydronaphtho-acridines.

Organic & biomolecular chemistry : 13 : 6269-6277 : DOI : 10.1039/c5ob00456j
Florence Mahuteau-Betzer (2015 May 12)

The French National Compound Library: advances and future prospects.

Médecine sciences : M/S : 31 : 417-22 : DOI : 10.1051/medsci/20153104016
Guillaume Kellermann, Markus Kaiser, Florent Dingli, Olivier Lahuna, Delphine Naud-Martin, Florence Mahuteau-Betzer, Damarys Loew, Evelyne Ségal-Bendirdjian, Marie-Paule Teulade-Fichou, Sophie Bombard (2015 May 11)

Identification of human telomerase assembly inhibitors enabled by a novel method to produce hTERT.

Nucleic acids research : 43 : e99 : DOI : 10.1093/nar/gkv425
Noëlie Campos, Renier Myburgh, Aude Garcel, Audrey Vautrin, Laure Lapasset, Erika Schläpfer Nadal, Florence Mahuteau-Betzer, Romain Najman, Pauline Fornarelli, Katjana Tantale, Eugénia Basyuk, Martial Séveno, Julian P Venables, Bernard Pau, Edouard Bertrand, Mark A Wainberg, Roberto F Speck, Didier Scherrer, Jamal Tazi (2015 Apr 19)

Long lasting control of viral rebound with a new drug ABX464 targeting Rev – mediated viral RNA biogenesis.

Retrovirology : 30 : DOI : 10.1186/s12977-015-0159-3

Année de publication : 2013

Delphine Naud-Martin, Xavier Martin-Benlloch, Florent Poyer, Florence Mahuteau-Betzer, Marie-Paule Teulade-Fichou (2013 Dec 11)

Acri-2,7-Py, a bright red-emitting DNA probe identified through screening of a distyryl dye library.

Biotechnology journal : 9 : 301-310 : DOI : 10.1002/biot.201300197
Blaise Dumat, Guillaume Bordeau, Elodie Faurel-Paul, Florence Mahuteau-Betzer, Nicolas Saettel, Germain Metge, Céline Fiorini-Debuisschert, Fabrice Charra, Marie-Paule Teulade-Fichou (2013 Aug 20)

DNA switches on the two-photon efficiency of an ultrabright triphenylamine fluorescent probe specific of AT regions.

Journal of the American Chemical Society : 135 : 12697-12706 : DOI : 10.1021/ja404422z

Année de publication : 2012

Ada Collura, Laetitia Marisa, Diletta Trojan, Olivier Buhard, Anaïs Lagrange, Arnaud Saget, Marianne Bombled, Patricia Méchighel, Mira Ayadi, Martine Muleris, Aurélien de Reynies, Magali Svrcek, Jean-François Fléjou, Jean-Claude Florent, Florence Mahuteau-Betzer, Anne-Marie Faussat, Alex Duval (2012 Sep 26)

Extensive characterization of sphere models established from colorectal cancer cell lines.

Cellular and molecular life sciences : CMLS : 2 : 729-42 : DOI : 10.1007/s00018-012-1160-9